Ovcar2

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August undefined, 2024

WebJun 18, 2008 · Ovarian cancer lines BG-1, UCI-101, HEY, OVCA420, OVCA432, OVCA433, OVCAR2, OVCAR3 and OVCAR5 cells were cultured in McCoy's 5A growth medium (Invitrogen) supplemented with 10% fetal bovine serum (FBS) and antibiotics (100 units/ml penicillin and 100 µg/ml streptomycin). WebApr 19, 2011 · The panel of ovarian tumor cell lines used consisted of OVCAR2, OVCAR3, OVCAR4, OVCAR5, OVCAR10, A2780, CP70, C30, PEO1, PEO4, SKOV3, and UPN251 , , . All tumor cells were cultured in RPMI 1640 medium supplemented with 10% FBS, 0.3 U/mL insulin, 2 mM L-glutamine, 100 U/mL penicillin, and 100 µg/mL streptomycin.

Targeting Dormant Ovarian Cancer Cells In Vitro and in an In Vivo …

WebApr 4, 2024 · Abstract. CCNE1 gene amplification is associated with overexpression of Cyclin E1 protein and is an important oncogenic driver. CCNE1 amplification is common in high grade serous ovarian carcinomas (HGSOC) and is associated with platinum resistance and poor patient outcomes. Importantly, Cyclin E1 overexpression can also occur in the … WebSep 16, 2024 · The invention provides B7-H3 targeting fusion proteins and methods of use thereof. The targeting fusion proteins include B7-H3 targeting tri-specific killer engager molecules comprising a B7-H3 targeting binding protein, a CD16 targeting binding protein, and an interleukin-15 protein. The methods of use thereof include methods of treating … basbun

Cellosaurus cell line OVCAR-2 (CVCL_3941)

WebApr 2, 2024 · Ovarian cancer is the most lethal gynaecological disease in women and, in 2024, there will be approximately 300,000 new diagnoses of ovarian cancer worldwide … WebLanguage Label Description Also known as; English: OVCAR-2. cell line WebObjective: Genomic studies of ovarian cancer (OC) cell lines frequently used in research revealed that these cells do not fully represent high-grade serous ovarian cancer (HGSOC), … svitici tabulka

OVCAR-4 Human Ovarian Cancer Cell Line SCC258

WebJan 5, 2024 · Nine cell lines with ≥2.9 colonies/microscopic field were categorized as having high tumorigenic potential, including PEO1, OVCAR8, OVARY1847, OV90, HEYA8, OVCAR2, CAOV2, HEY, and HEYC2. Nonadherent spheroid culture conditions have been used to enrich for CSLCs from tumor tissue of a variety of malignancies ( 11–13 ). WebJul 17, 2024 · In order to be effective models to identify biomarkers of chemotherapy response, cancer cell lines require thorough characterization. In this study, we … svitici srdickoWebMay 24, 2013 · OVCAR2 cells did not exhibit enriched binding of CTCF to the intron 3 CTCF binding motif relative to the control, while CAOV2 and HEY showed ∼2.2 to 3.8-fold enrichment of CTCF binding (Figure 5E). BORIS Binding at the IGF2 Intron 3 CTCF Site. We also determined if the BORIS protein (encoded by CTCFL) binds at the CTCF motif. bas bundaberg

"WebIntroduction. The Hippo pathway is known to regulate cell proliferation and organ size in both Drosophila and mammals. In mammals, the Hippo pathway consists of a highly conserved kinase cascade, whose upstream proteins SAV1, MST1/2, and LATS1/2 together form a complex to phosphorylate the key transcriptional coactivator Yes-associated … " - Ovcar2

Ovcar2

Identification of ovarian high-grade serous carcinoma cell …

WebNIH:OVCAR-3 [OVCAR3] HTB-161 ™. NIH:OVCAR-3 [OVCAR3] are epithelial cells that were isolated in 1982 from the malignant ascites of a patient with progressive adenocarcinoma … WebNIH:OVCAR-2; OVCAR2; OVCAR 2: Accession: CVCL_3941: Resource Identification Initiative: To cite this cell line use: OVCAR-2 (RRID:CVCL_3941) Comments: Omics: SNP array …

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WebInvitrogen Anti-NOTCH3 Polyclonal, Catalog # PA5-89283. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody reacts with Human, Mouse, Rat samples. Supplied as 100 µL purified antibody (1.35 mg/mL). WebJul 1, 2024 · Ovarian cancer remains a significant challenge in women worldwide. Tumors of the high-grade serous carcinoma (HGSC) type represent the most common form of the …

WebSep 13, 2024 · The primary aim of the current study was to investigate the antitumor effects of ferruginol in OVCAR‑3 human ovary cancer cells. The effects of ferruginol on cell apoptosis, cell migration and cell cycle phase distribution were also evaluated. Cell cytotoxicity induced by ferruginol was determined by an MTT assay, while fluorescence … WebJun 6, 2024 · MicroRNAs (miRNAs) often display different expression in many cancers and other diseases in current research studies. miR-223 expression is upregulated in rheumatoid arthritis. Also, miR-223 expression has been demonstrated to be highly expressed in pancreatic cancer and gastric cancer in comparison with normal tissue. However, whether …

WebUser's Publication: 21122 Ideo H, Tsuchida A, Takada Y, Kinoshita J, Inaki N, Minamoto T. Suppression of galectin-4 attenuates peritoneal metastasis of poorly differentiated gastric cancer cells. Gastric Cancer 2024 PubMed ID: 36695981 DOI: 10.1007/s10120-023-01366-5 WebAntibodies that recognize cancer biomarkers, such as MUC16, can be used as vehicles to deliver contrast agents (imaging) or cytotoxic payloads (therapy) to the site of tumors. MUC16 is overexpressed in 80% of epithelial ovarian cancer (EOC) and 65% of pancreatic ductal adenocarcinomas (PDAC), where effective ‘theranostic’ probes are …

WebMay 24, 2013 · HEY cells (A), OVCAR2 cells (B) and CAOV2 cells (C) were analyzed in sextuplicate at 48 h (light gray) and 72 h (dark gray) post-plasmid transfection. pGL3, control plasmid with no insert; pGL3-GAPDH, plasmid with sequence fragment of the GAPDH locus that does not contain a consensus CTCF binding motif; pGL3-CTCF, plasmid with the IGF2 …

WebOVCAR2: Sample type: RNA : Source name: Ovary: Organism: Homo sapiens: Characteristics: Ovarian serous carcinoma (ascites) Gender: female: Treatment protocol: … bas bundestagWebMar 1, 2005 · OVCAR2 and PEO4 cells were pretreated with 50 μ M AG490 followed by treatment with a range of platinum concentrations. AMD473 sensitivity was enhanced 4.1-fold in PEO4 cells ( P =0.001) and 9.1-fold in OVCAR2 cells ( … svitici vlacekWebDec 11, 2024 · The bromoalkane, 1-bromopropane (1-BP), may damage the reproductive system though oxidative stress, while the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) plays an important role in regulating intracellular antioxidant levels against oxidative stress. bas bumpWebNational Center for Biotechnology Information bas bundesamtWebFeb 23, 2015 · All other cell lines (A2008, OAW42, OVCAR2, OVCAR3, OVCAR4, OVCAR5, OVCAR8, OVCAR10, PE01, PE04, SKOV3) were obtained from the Ovarian Cancer Research Center cell bank at UPENN with documented and cited origin, thus were not re-authenticated at the time of the study . svitici tetovaniWeb(A) IGF2 transcription levels in each cell line; (B) IGF2 intron 3 region methylation levels; (C) ChIP assay for binding of CTCF to the MYC locus in CAOV2 and OVCAR2 cells (HEY cells were not ... bas burlageWebOVCAR2, OVCAR3, OVCAR4, PEO1, and PEO4 (Figure 1C). In contrast, A2780, and its platinum resistant sub-clones, CP70 and C30 cells [32] presented less tight clustering and matrix modification phenotypes similar to the ones observed in OVCAR10 (Figure 1E). A2780 cells also showed a degree of heterogeneity in their modifying effects on the ... svitici vanocni stromek