Das Helix-Turn-Helix-Motiv (HTH) ist ein Sekundärstrukturelement in Proteinen. Es ist Bestandteil von DNA-bindenden Proteinen mit sequenzspezifischer DNA-Bindedomäne und setzt sich aus zwei α-Helices zusammen, die durch eine β-Schleife (auch β-turn) verbunden sind. Transkriptionsregulatoren in Bakterien enthalten oft ein HTH-Motiv. Homöodomänen enthalten ein Helix-Turn-Helix-M… Web5 feb. 1989 · The importance of the helix-turn-helix motif in DNA-protein interaction has been supported by a wealth of biochemical and genetic evidence (e.g. see Refs. 15-18) and has now been shown directly by recent structure determinations a number of complexesof repressor of proteins with synthetic operators. These include the DNA-binding domains …
DNA Binding Motifs Flashcards Quizlet
WebThe helix–turn–helix (HTH) structure was the first DNA-recognition motif identified in which an α-helical region is followed by a sharp β-turn and then another α-helical region. The … WebThe EMBO journal. 1995. TLDR. The crystal structure of endonuclease III, combined with mutational analysis, suggests the structural basis for the DNA binding and catalytic activity of the enzyme and identifies Helix‐hairpin‐helix and FCL motifs, which may be a recurrent structural theme for DNA binding proteins. 439. down pillows meaning
Beta hairpin - Wikipedia
WebOnce the initial turn has been established, two mechanisms have been proposed as to how the rest of the beta-hairpin folds: a hydrophobic collapse with side-chain level rearrangements, or the more accepted zipper-like mechanism. [4] The β-hairpin loop motif can be found in many macromolecular proteins. WebHelix-loop-helix Consists of alpha helices bound by a looping stretch of amino acids. This motif is seen in transcription factors. Zinc finger Two beta strands with an alpha helix … Web7 apr. 2024 · helix-turn-helix-Motiv s, Helix-turn-helix-Motiv, HTH-Motiv, ein zuerst in bakteriellen Proteinen entdecktes Strukturmotiv DNA-bindender Proteine (Protein-DNA … down pillows makeover